LAboratoire de Spectrochimie Infrarouge et Raman – UMR 8516
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Projects in Ultrafast & Photo-Nanoscopy

LASIRSymposium_Ultrafast-MicroscopyContact: Michel Sliwa


Sparse deconvolution of high-density super-resolution images
S. Hugelier et al.
Scientific Reports, 2016, 6 | DOI

Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP
J-P. Colletier et al.
J. Phys. Chem. Lett., 2016, 7 | DOI

  • Oct 2016 New Japanese Ph.D. guest
  • July 2016 New invited Professor & Researcher
  • April 2016 New post doctorate
  • March 2016 New project accepted, Defi Imag’In
  • Feb 2016 New publication in J. Phys. Chem. Lett.
  • Jan 2016 New publication in Scientific Report

ANR Ultrafast Nanoscopy (2014-2018), PI M. Sliwa

Understanding energy and charge carrier dynamics in fluorescent
organic nanoparticles: Ultrafast and high resolution microscopy


The first goal of this project is to develop new ultrafast optical techniques with nanometric resolution to be able to understand the emission dynamics of organic fluorescent nanoparticles at nanometer scale. Secondly, the project should also lead to the development of new fluorescent probes. In addition, the development of adhoc advanced data analysis methods will be required for biological imaging applications. The last challenge will be to use the different ultrafast microscopy systems to characterize (energy / electron transfer) the different synthesized nanoparticles in different biological environments.

Défi Imag’In 2016, Qnanoscopy, PI C. Ruckebusch
Development of quantitative methods of treatment and analysis of images for the non-conventional modalities of imaging, in particular the imaging of fluorescence of unique molecules and the 3D tomography

PHC Tournesol, PI C. Ruckebusch, Co-PI P. Dedecker KUL
Quantitative nanoscale fluorescence imaging of high density samples

Programme IFD – Université of Coppenhagen, PI C. Ruckebusch
A chemometric framework for multiscale multispectral micro- and nano-imaging


ANR BioXFEL (Co-investigateur ANR Défi de tous les savoirs 2015-2019)
PI M. Weik IBS Grenoble, Co-PI M. Cammarata U. Rennes, S. Boutet LCLS Stanford
Elucidating structural intermediates of fluorescent proteins using X-ray free electron lasers and ultra-fast UV-visible and infrared spectroscopies

ANR Blink (PRCE 2015-2019)
PI C. Coudret U. Toulouse, Co-PI F. Gauffre U. Rennes, Entreprise: Anton-Paar-France
Multi-luminescent up-converting nanohybrids with controlled blinking for super-resolution imaging and single particle tracking


Pr. Syoji Ito, Osaka University, Pr. H. Miyasaka Lab
Dr. Katsuya Mutoh, Aoyama Gakuin University, Pr. J. Abe Lab
Yuki Horiuchi, Yamagata University, Pr. J-I. Hotta Lab