LAboratoire de Spectrochimie Infrarouge et Raman – UMR 8516
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Article in “Nature Chemistry”

september 2017

Scientists at LASIR (Lille 1), Institut de Biologie Structurale, Rennes 1 and Paris-Sud, as well as the Max-Planck Institute in Heidelberg, Germany, have observed the real-time switching of a fluorescent protein using a brand new generation of X-ray source, the free electron lasers (XFEL). This observation, confirmed by simulations, allowed researchers to make hypotheses about the photo-switching mechanism of the protein. These hypotheses could then be verified with directed mutagenesis.

These works are published in Nature Chemistry on September 11,2017.